Introduction to MicroStrong Nutrition Test Science


What this package contains:

Your personal genetic snapshot
The first section of your report contains a listing of the genes we test for and your individual genotype for each one. It contains information about your requirements for dietary antioxidants, your need for anti-inflammatory omega-3 and -6 fats, and how efficiently your body detoxifies active carcinogens. This information can be used to construct a nutritional supplement program suited to your unique needs.

More information about the genes we test for This section goes into greater detail about each of the genes we test for. The role of each gene is explained in greater detail, including how mutations can impact the way your body responds to different types and amounts of nutritional supplements. Also included are specific behaviors which will have positive or negative impacts on your long term health. Remember: there are no bad genes, only bad choices! The detailed information in this section will help you make the best choices possible for your personal genotype.

We test for variations in 12 key genes that are very important in your body’s general health: specifically your genetic susceptibility for: Cholesterol Oxidative stress, Environmental challenges, Cardiovascular health, Detoxification, Immune health, Neurological health, Pulmonary health, Bone health, Lung and Breast Tissue health, Blood Pressure, Aging.

By knowing variations in your genes we can answer the question what are your genetic vulnerabilities. This knowledge can be used to build your Personal Supplements Program specifically for your genotype.


Bone Strength: Bone density is influenced by environmental and genetic effects. Approximately 75% of the genetic influence in healthy people is from the Vitamin D Receptor, or VDR. There tends to be a lower bone mineral density when variation in the VDR gene are present than when they are not. This results in weaker bones. The VDR gene may also have influence on other aspects such as young adult growth, blood sugar regulation, normal cell division, and parathyroid hormone production.
Sample supplement ingredients: Calcium, Vitamin K1, Vitamin D3.

Detox: Microsomal Epoxide Hydrolase (EPHX) is an enzyme which aids in the detoxification of foreign, highly reactive toxic compounds (called epoxides) such as car exhaust, wood smoke, cigarette smoke, pesticides and alcohol. A variation in the EPHX gene causes the gene to have lower activity, which will make it more difficult for a person to detoxify harmful substances, causing them to be more vulnerable to the effects of the epoxide.

Sample supplement ingredients: Milk thistle extract, Green Tea extract, Broccoli extract and others.

CoQ10: Coenzyme Q10 Reductase (NQ10) is responsible for the production of the coenzyme which removes free radicals in specific areas of a cell. Free radicals are considered to play a large role in the process of aging. A variation in the NQ01 gene results in a reduced rate of production of the functional coenzyme, causing carriers to have higher levels of free radicals present in their bloodstream.

Sample Supplement ingredients: Ubiquinone or Ubiquinol (depending on what form your body metabolizes, found by running a genetic test).

Superoxide: The Maganese Superoxide Dimutase (SOD2) is an enzyme responsible for the removal of superoxide free radical. The superoxide is made up of two oxygen molecules, one having a negative charge. It is produced in all cells, and SOD2 is the only enzyme in the mitochondria that can neutralize it. Variation in this gene can result in an individual having a weaker defense against free radicals.

Sample supplement ingredients: Spirulina Powder, Green Tea extract, Vitamin B3 and others.

Lung and Breast Tissue: Glutathione Peroxidase 1 (GPX1) is an antioxidant enzyme that removes hydrogen peroxide. The enzyme absorbs selenium into its protein structure, so the amount present depends on an individual’s selenium levels. Variation in the gene can cause a reduced ability to absorb the selenium, resulting in a larger selenium intake needed to achieve the same results with respect to hydrogen peroxide removal. The removal of hydrogen peroxide helps to protect sensitive tissues such as lung and breast tissues.

Sample supplement ingredients: Citrus limonium, Citrus paradise and Citrus sinensis, Milk Thistle extract, and others.

Collagen Health: Collagen is a fibre that is made and broken down in a continuous cycle and is the main component of connective tissues. The enzyme that breaks down collagen is MMP1 (Matrix Metalloproteinase). A variation in the MMP1 gene causes the protein to produced at a higher rate, resulting in the collagen being broken down faster than it is made. This can cause problems in the bones and joints.

Sample supplement ingredients: Tomato powder, White Tea Extract, Grape Seed extract.

Cardiovascular: Homocysteine is a chemical produced by reactions in the body. The Methionine Synthase Reductase (MTRR) enzyme is one of the ways that the levels of homocysteine are regulated (it transforms it back into Methionine or cysteine). This helps the body to preserve cardiovascular health. A variation the MTRR gene in certain population groups decreases the ability of the individuals to remove homocystein from blood.

Sample supplement ingredients: Zinc, Vitamin B3, Vitamin B2, and others.

Cardiovascular Enzyme: the MTHFR (Methylene Tetrahydrofolate Reductase) is another enzyme that reduces levels of homocysteine in the blood. A variation in the gene causes the enzyme to be unable to remove homocysteine efficiently, causing higher levels to be present in the blood.

Sample supplement ingredients: Trimethylglycine, Choline Bitartrate, L-methlyfolate.

Inflammation Response: The Tumor Necrosis Factor – a (TNF-a) is a chemical in the immune system that is partly responsible for inflammatory processes. Inflammation occurs when the immune system responds to a perceived attack on the body. A variation in the TNF-a gene can cause the immune system to be overactive, which can cause stiffness and soreness in the joints.

Sample supplement ingredients: Milk Thistle extract, Green Tea extract, Pomegranate extract, and others.

Cholesterol Oxidation: When the low density lipoprotein (LDL) becomes oxidized, it is believed that it can no longer transport cholesterol through the blood stream as efficiently. The PON1 (Paraxonase 1) enzyme attaches itself to the high-density lipoprotein (HDL), which allows it to protect both the HDL and the LDL from oxidation. Variations in the PON1 gene cause lower levels of PON1 to be present, resulting in higher levels of oxidized LPL, which can negatively effect cardiovascular health.

Sample supplement ingredients: Organic Reshi Mushroom extract, Shitake Mushroom extract, Vitamin E, and others.

Cholesterol: One of the components of the low-density lipoprotein (LDL) is Apolipoprotein B (ApoB). Variation on the ApoB gene cause higher than normal levels of ApoB to be present. This results in an increase in the levels of cholesterol along with decreased tolerance of glucose.

Sample supplement ingredients: Pomegranate extract, Artichoke extract, and others.

Blood Pressure: Aldosterone synthase is an enzyme encoded on the CYP11B2 gene, and plays a role in the regulation of blood pressure. A loss of the ability for blood vessels to relax and constrict in response to different demands for blood flow can be a result of a variation on the CYP11B2 gene. This inability of the vessels to react to the needs of the body can have a long term effect of problems in cardiovascular tissues.

Sample supplement ingredients: Potassium, Magnesium, Acerola Cherry extract, and others.